Easing Chronic Fatigue Syndrome and Fibromyalgia Symptoms

How we get up in the morning is usually overlooked or taken for granted. Many of us spring, roll, or even crawl out from under the covers without considering what a privilege that experience is. Regardless of the seeming struggle that comes with the rising sun, it pales in comparison to the experience of those with fibromyalgia or chronic fatigue syndrome (CFS). These conditions are long-lasting and impact nearly every part of the body. Not only are these problems difficult to resolve but they also bring incredibly debilitating and painful symptoms.

A common problem associated with both diseases is extreme fatigue that may make even the simplest of tasks, like getting out of bed, a seemingly impossible feat. Intense fatigue is only one of the many problems associated with these conditions. Unfortunately, many physicians don’t know where to begin when it comes to treating these chronic conditions. Recognizing the signs, symptoms, and causes of fibromyalgia and CFS is the only way to move forward and acquire effective treatment.

Recognizing CFS and Fibromyalgia

Diagnosing chronic conditions such as CFS and fibromyalgia can be difficult because many of the symptoms may be caused by a variety of other conditions. CFS and fibromyalgia are particularly complex because they share numerous symptoms. Furthermore, up to 70 percent of patients suffering from one of the conditions also has the other. Some of the common symptoms shared between the two diseases include:

  • Restless and non-restorative sleep
  • Fatigue that is not resolved by resting
  • Pain and stiffness in the muscles and joints
  • Headaches
  • Flu-like symptoms
  • Sore throat
  • Easily fatigued after even minor exertion
  • Weight gain
  • Difficulty thinking clearly and easily confused
  • Poor concentration
  • Digestive problems

Distinguishing between CFS and Fibromyalgia requires inspection of the specific systems impacted. CFS involves pituitary malfunction, whereas fibromyalgia primarily impacts the hypothalamus. Both glands are critical in regulating hormone function and have differing degrees of influence over the nervous system. It is not surprising that so many patients who experience one of these conditions also have the other because the hypothalamus and pituitary are mutually influential on one another.

Digging Deeper into CFS and Fibromyalgia

The primary complaint from those with these chronic conditions is a severe lack of energy. Studies have shown that those with CFS and fibromyalgia have 20 percent less energy in their muscles, which not only contributes to overall feelings of fatigue, but also promotes muscle pain and aches. Resolving this extreme fatigue requires inspecting one’s energy production at the cellular level.

Mitochondria, sometimes called the furnaces of the cells, are responsible for producing cellular energy. One study composed of CFS patients showed that 80% of the participants had reduced mitochondrial function. With defective or inefficient mitochondria, the body can quickly fall into an energy deficit. Furthermore, defunct mitochondria significantly reduce cellular metabolism, which makes it increasingly difficult to restore energy levels. Poor cellular metabolism means that the body burns fuel and energy faster than it can be produced. This results in fatigue, soreness, pain, stiffness, and an inability to regain energy.

Both systems affected by CFS and fibromyalgia, the hypothalamus and pituitary, are particularly sensitive to mitochondrial dysfunction. Damage to the mitochondria can happen in a variety of ways. The most common source of mitochondrial damage is from pesticides, chronic infections, and nutritional and hormonal deficiencies. The mitochondria affect a variety of systems such as the brain, heart, skeletal muscles, liver, and endocrine system. This partially explains why CFS and fibromyalgia have such a significant impact on the body.

Because mitochondria are such pivotal elements in the occurrence of CFS and fibromyalgia, it is important that they are effectively treated and optimized. There are few substances as effective at improving mitochondrial function than D-Ribose.

Reducing Symptoms with D-Ribose

Promoting mitochondrial function can seem like a daunting task but the answer may be found in a substance that is already produced naturally in the body. D-Ribose is a form of sugar that the body utilizes to produce adenosine triphosphate, otherwise known as ATP. Increasing one’s ATP supports cellular metabolism and thus the creation of energy.

Multiple studies have been done that show D-Ribose does indeed improve cellular energy, particularly within the heart and skeletal muscles. Jacob Teitelbaum, M.D. and author of “The Fatigue and Fibromyalgia Solution,” conducted a study in 2006 to identify the correlation between D-Ribose, fibromyalgia, and CFS. During the study patients were given D-Ribose over a set period. These participants presented significant improvement in the areas of energy, sleep, mental clarity, pain, and overall well-being. Nearly 66 percent of those who took part in the study stated that they experienced significant improvement of their symptoms.

In 2012, doctor Teitelbaum headed another study that showed similar results. 257 patients took 5 grams of D-Ribose three times a day over three weeks. Of that group, there was an average energy increase of 61 percent. Participants also reported improved sleep quality, reduced pain, greater mental clarity and well-being.

With such positive results, one may wonder how to best acquire D-Ribose and support their mitochondria.

The HoltraCeutical Answer

HoltraCeuticals produces two supplements, Ribomax M and Flex Plus, intended to be taken together to support mitochondrial health and combat the symptoms of CFS and Fibromyalgia.

Ribomax M is specifically formulated to restore the body’s energy stores in response to depletion caused by CFS and/or Fibromyalgia. The primary ingredient of this supplement is D-Ribose, which, as we know from reading above, has an impressive positive impact on energy levels. However, diabetics may be at risk of blood sugar imbalances when taking supplements containing D-Ribose. Those at risk of developing diabetes or currently diagnosed with the condition should speak to a physician before supplementing with D-Ribose.

Flex Plus is the other piece of this powerful supplemental combination. This formulation is intended to increase mitochondrial function. Optimizing cellular energy production is a significant contributor in combatting CFS and Fibromyalgia. Flex Plus contains Glucuronolactone, which is a naturally produced substance, much like D-Ribose. Glucuronolactone is a fuel source that is created when the liver metabolizes glucose.

When taken together, Ribomax M and Flex Plus empower mitochondria and help restore muscular energy. By supporting cellular metabolism, muscle energy, and mitochondrial health, Ribomax M and Flex Plus provide significant relief of CFS and fibromyalgia symptoms. Through proper supplementation and effective treatment with a multi-system approach the debilitating and frustrating conditions of CFS and fibromyalgia can be resolved.


1. https://www.ncbi.nlm.nih.gov/pubmed/17109576

2. http://fedupwithfatigue.com/d-ribose-fibromyalgia/

3. https://www.highbeam.com/doc/1G1-192102228.html

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